Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor

Dysregulations of lipid metabolism in the liver may trigger steatosis progression, leading to potentially severe clinical consequences such as nonalcoholic fatty liver diseases (NAFLDs). Molecular mechanisms underlying liver lipogenesis are very complex and fine-tuned by chromatin dynamics and multi...

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Detalles Bibliográficos
Autores principales: Personnaz, Jean, Piccolo, Enzo, Dortignac, Alizée, Iacovoni, Jason S., Mariette, Jérôme, Rocher, Vincent, Polizzi, Arnaud, Batut, Aurélie, Deleruyelle, Simon, Bourdens, Lucas, Delos, Océane, Combes-Soia, Lucie, Paccoud, Romain, Moreau, Elsa, Martins, Frédéric, Clouaire, Thomas, Benhamed, Fadila, Montagner, Alexandra, Wahli, Walter, Schwabe, Robert F., Yart, Armelle, Castan-Laurell, Isabelle, Bertrand-Michel, Justine, Burlet-Schiltz, Odile, Postic, Catherine, Denechaud, Pierre-Damien, Moro, Cédric, Legube, Gaelle, Lee, Chih-Hao, Guillou, Hervé, Valet, Philippe, Dray, Cédric, Pradère, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956270/
https://www.ncbi.nlm.nih.gov/pubmed/35333579
http://dx.doi.org/10.1126/sciadv.abg9055

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