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The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees

Transcutaneous osseointegration for amputees (TOFA) refers to an intramedullary metal endoprosthesis which passes transcutaneously to connect with a limb exoprosthesis. The first recognizably modern experiments and attempts occurred in the 1940s. Multiple researchers using a plethora of materials an...

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Autores principales: Hoellwarth, Jason Shih, Tetsworth, Kevin, Akhtar, Muhammad Adeel, Al Muderis, Munjed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956382/
https://www.ncbi.nlm.nih.gov/pubmed/35340813
http://dx.doi.org/10.1155/2022/7960559
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author Hoellwarth, Jason Shih
Tetsworth, Kevin
Akhtar, Muhammad Adeel
Al Muderis, Munjed
author_facet Hoellwarth, Jason Shih
Tetsworth, Kevin
Akhtar, Muhammad Adeel
Al Muderis, Munjed
author_sort Hoellwarth, Jason Shih
collection PubMed
description Transcutaneous osseointegration for amputees (TOFA) refers to an intramedullary metal endoprosthesis which passes transcutaneously to connect with a limb exoprosthesis. The first recognizably modern experiments and attempts occurred in the 1940s. Multiple researchers using a plethora of materials and techniques over the following 50 years identified principles and obstacles which informed the first long-term successful surgery in 1990. Unfortunately, the current mainstream TOFA literature presents almost exclusively subsequent developments, generally omitting prior research, leading to some historical mistakes being repeated. Given the increasing interest and surgical volume of TOFA, this literature review was performed to delineate TOFA's basic science and surgical origins and to integrate these early efforts within the contemporary understanding. Studying this research could protect and benefit future patients, surgeons, and implant developers as TOFA is entering a phase of increased attention and innovation. The aim of this article is to provide a focused reference of foundational research, much of which is difficult to identify and retrieve, for clinicians and researchers.
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spelling pubmed-89563822022-03-26 The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees Hoellwarth, Jason Shih Tetsworth, Kevin Akhtar, Muhammad Adeel Al Muderis, Munjed Adv Orthop Review Article Transcutaneous osseointegration for amputees (TOFA) refers to an intramedullary metal endoprosthesis which passes transcutaneously to connect with a limb exoprosthesis. The first recognizably modern experiments and attempts occurred in the 1940s. Multiple researchers using a plethora of materials and techniques over the following 50 years identified principles and obstacles which informed the first long-term successful surgery in 1990. Unfortunately, the current mainstream TOFA literature presents almost exclusively subsequent developments, generally omitting prior research, leading to some historical mistakes being repeated. Given the increasing interest and surgical volume of TOFA, this literature review was performed to delineate TOFA's basic science and surgical origins and to integrate these early efforts within the contemporary understanding. Studying this research could protect and benefit future patients, surgeons, and implant developers as TOFA is entering a phase of increased attention and innovation. The aim of this article is to provide a focused reference of foundational research, much of which is difficult to identify and retrieve, for clinicians and researchers. Hindawi 2022-03-18 /pmc/articles/PMC8956382/ /pubmed/35340813 http://dx.doi.org/10.1155/2022/7960559 Text en Copyright © 2022 Jason Shih Hoellwarth et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hoellwarth, Jason Shih
Tetsworth, Kevin
Akhtar, Muhammad Adeel
Al Muderis, Munjed
The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title_full The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title_fullStr The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title_full_unstemmed The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title_short The Clinical History and Basic Science Origins of Transcutaneous Osseointegration for Amputees
title_sort clinical history and basic science origins of transcutaneous osseointegration for amputees
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956382/
https://www.ncbi.nlm.nih.gov/pubmed/35340813
http://dx.doi.org/10.1155/2022/7960559
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