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Functional antagonism between ΔNp63α and GCM1 regulates human trophoblast stemness and differentiation

The combination of EGF, CHIR99021, A83-01, SB431542, VPA, and Y27632 (EGF/CASVY) facilitates the derivation of trophoblast stem (TS) cells from human blastocysts and first-trimester, but not term, cytotrophoblasts. The mechanism underlying this chemical induction of TS cells remains elusive. Here we...

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Detalles Bibliográficos
Autores principales:	Wang, Liang-Jie, Chen, Chie-Pein, Lee, Yun-Shien, Ng, Pui-Sze, Chang, Geen-Dong, Pao, Yu-Hsuan, Lo, Hsiao-Fan, Peng, Chao-Hsiang, Cheong, Mei-Leng, Chen, Hungwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956607/ https://www.ncbi.nlm.nih.gov/pubmed/35338152 http://dx.doi.org/10.1038/s41467-022-29312-6

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