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Complex roles of nicotinamide N-methyltransferase in cancer progression

Nicotinamide N-methyltransferase (NNMT) is an intracellular methyltransferase, catalyzing the N-methylation of nicotinamide (NAM) to form 1-methylnicotinamide (1-MNAM), in which S-adenosyl-l-methionine (SAM) is the methyl donor. High expression of NNMT can alter cellular NAM and SAM levels, which in...

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Detalles Bibliográficos
Autores principales:	Wang, Weixuan, Yang, Changmei, Wang, Tianxiang, Deng, Haiteng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956669/ https://www.ncbi.nlm.nih.gov/pubmed/35338115 http://dx.doi.org/10.1038/s41419-022-04713-z

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