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Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand

Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region. Indoor ra...

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Autores principales: Somsunun, Kawinwut, Prapamontol, Tippawan, Pothirat, Chaicharn, Liwsrisakun, Chalerm, Pongnikorn, Donsuk, Fongmoon, Duriya, Chantara, Somporn, Wongpoomchai, Rawiwan, Naksen, Warangkana, Autsavapromporn, Narongchai, Tokonami, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956686/
https://www.ncbi.nlm.nih.gov/pubmed/35338199
http://dx.doi.org/10.1038/s41598-022-09122-y
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author Somsunun, Kawinwut
Prapamontol, Tippawan
Pothirat, Chaicharn
Liwsrisakun, Chalerm
Pongnikorn, Donsuk
Fongmoon, Duriya
Chantara, Somporn
Wongpoomchai, Rawiwan
Naksen, Warangkana
Autsavapromporn, Narongchai
Tokonami, Shinji
author_facet Somsunun, Kawinwut
Prapamontol, Tippawan
Pothirat, Chaicharn
Liwsrisakun, Chalerm
Pongnikorn, Donsuk
Fongmoon, Duriya
Chantara, Somporn
Wongpoomchai, Rawiwan
Naksen, Warangkana
Autsavapromporn, Narongchai
Tokonami, Shinji
author_sort Somsunun, Kawinwut
collection PubMed
description Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region. Indoor radon concentrations were measured in 192 houses in eight provinces of UNT. Indoor radon concentrations ranged from 11 to 405 Bq m(−3) and estimated annual effective dose ranged from 0.44 to 12.18 mSv y(−1). There were significant differences in indoor radon concentrations between the houses of lung cancer cases and healthy controls (p = 0.033). We estimated that 26% of lung cancer deaths in males and 28% in females were attributable to indoor radon exposure in this region. Other factors influencing indoor radon levels included house characteristics and ventilation. The open window-to-wall ratio was negatively associated with indoor radon levels (B = −0.69, 95% CI −1.37, −0.02) while the bedroom location in the house and building material showed no association. Indoor radon hence induced the fractal proportion of lung cancer deaths in UNT.
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spelling pubmed-89566862022-03-28 Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand Somsunun, Kawinwut Prapamontol, Tippawan Pothirat, Chaicharn Liwsrisakun, Chalerm Pongnikorn, Donsuk Fongmoon, Duriya Chantara, Somporn Wongpoomchai, Rawiwan Naksen, Warangkana Autsavapromporn, Narongchai Tokonami, Shinji Sci Rep Article Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region. Indoor radon concentrations were measured in 192 houses in eight provinces of UNT. Indoor radon concentrations ranged from 11 to 405 Bq m(−3) and estimated annual effective dose ranged from 0.44 to 12.18 mSv y(−1). There were significant differences in indoor radon concentrations between the houses of lung cancer cases and healthy controls (p = 0.033). We estimated that 26% of lung cancer deaths in males and 28% in females were attributable to indoor radon exposure in this region. Other factors influencing indoor radon levels included house characteristics and ventilation. The open window-to-wall ratio was negatively associated with indoor radon levels (B = −0.69, 95% CI −1.37, −0.02) while the bedroom location in the house and building material showed no association. Indoor radon hence induced the fractal proportion of lung cancer deaths in UNT. Nature Publishing Group UK 2022-03-25 /pmc/articles/PMC8956686/ /pubmed/35338199 http://dx.doi.org/10.1038/s41598-022-09122-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Somsunun, Kawinwut
Prapamontol, Tippawan
Pothirat, Chaicharn
Liwsrisakun, Chalerm
Pongnikorn, Donsuk
Fongmoon, Duriya
Chantara, Somporn
Wongpoomchai, Rawiwan
Naksen, Warangkana
Autsavapromporn, Narongchai
Tokonami, Shinji
Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title_full Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title_fullStr Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title_full_unstemmed Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title_short Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
title_sort estimation of lung cancer deaths attributable to indoor radon exposure in upper northern thailand
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956686/
https://www.ncbi.nlm.nih.gov/pubmed/35338199
http://dx.doi.org/10.1038/s41598-022-09122-y
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