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Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity

Representative models are needed to screen new therapies for patients with cancer. Cancer organoids are a leap forward as a culture model that faithfully represents the disease. Mouse-derived cancer organoids (MDCOs) are becoming increasingly popular, however there has yet to be a standardized metho...

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Detalles Bibliográficos
Autores principales: DeStefanis, Rebecca A., Kratz, Jeremy D., Olson, Autumn M., Sunil, Aishwarya, DeZeeuw, Alyssa K., Gillette, Amani A., Sha, Gioia C., Johnson, Katherine A., Pasch, Cheri A., Clipson, Linda, Skala, Melissa C., Deming, Dustin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956720/
https://www.ncbi.nlm.nih.gov/pubmed/35338174
http://dx.doi.org/10.1038/s41598-022-08937-z