Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice

Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. It has been hypothesized that normal aging and age-related diseases such as Parkinson’s disease are in part due to modest decrease in expression of mitochondrial complex I subunits....

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Detalles Bibliográficos
Autores principales: McElroy, Gregory S., Chakrabarty, Ram P., D’Alessandro, Karis B., Hu, Yuan-Shih, Vasan, Karthik, Tan, Jerica, Stoolman, Joshua S., Weinberg, Samuel E., Steinert, Elizabeth M., Reyfman, Paul A., Singer, Benjamin D., Ladiges, Warren C., Gao, Lin, Lopéz-Barneo, José, Ridge, Karen, Budinger, G. R. Scott, Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956724/
https://www.ncbi.nlm.nih.gov/pubmed/35338200
http://dx.doi.org/10.1038/s41598-022-09074-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956724/
https://www.ncbi.nlm.nih.gov/pubmed/35338200
http://dx.doi.org/10.1038/s41598-022-09074-3

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