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A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens
The emergence of multidrug-resistant (MDR) Gram-negative pathogens is an urgent global medical challenge. The old polymyxin lipopeptide antibiotics (polymyxin B and colistin) are often the only therapeutic option due to resistance to all other classes of antibiotics and the lean antibiotic drug deve...
Autores principales: | Roberts, Kade D., Zhu, Yan, Azad, Mohammad A. K., Han, Mei-Ling, Wang, Jiping, Wang, Lynn, Yu, Heidi H., Horne, Andrew S., Pinson, Jo-Anne, Rudd, David, Voelcker, Nicolas H., Patil, Nitin A., Zhao, Jinxin, Jiang, Xukai, Lu, Jing, Chen, Ke, Lomovskaya, Olga, Hecker, Scott J., Thompson, Philip E., Nation, Roger L., Dudley, Michael N., Griffith, David C., Velkov, Tony, Li, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956739/ https://www.ncbi.nlm.nih.gov/pubmed/35338128 http://dx.doi.org/10.1038/s41467-022-29234-3 |
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