Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion

BACKGROUND & AIMS: Hepatic stellate cells (HSCs) are the primary cell type in liver fibrosis, a significant global health care burden. Cytoglobin (CYGB), a globin family member expressed in HSCs, inhibits HSC activation and reduces collagen production. We studied the antifibrotic properties of g...

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Detalles Bibliográficos
Autores principales: Hieu, Vu Ngoc, Thuy, Le Thi Thanh, Hai, Hoang, Dat, Ninh Quoc, Hoang, Dinh Viet, Hanh, Ngo Vinh, Phuong, Dong Minh, Hoang, Truong Huu, Sawai, Hitomi, Shiro, Yoshitsugu, Sato-Matsubara, Misako, Oikawa, Daisuke, Tokunaga, Fuminori, Yoshizato, Katsutoshi, Kawada, Norifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956869/
https://www.ncbi.nlm.nih.gov/pubmed/35334247
http://dx.doi.org/10.1016/j.redox.2022.102286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956869/
https://www.ncbi.nlm.nih.gov/pubmed/35334247
http://dx.doi.org/10.1016/j.redox.2022.102286

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