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The impact of noise and missing fragmentation cleavages on de novo peptide identification algorithms

Proteomics aims to characterise system-wide protein expression and typically relies on mass-spectrometry and peptide fragmentation, followed by a database search for protein identification. It has wide ranging applications from clinical to environmental settings and virtually impacts on every area o...

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Detalles Bibliográficos
Autores principales: McDonnell, Kevin, Howley, Enda, Abram, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956878/
https://www.ncbi.nlm.nih.gov/pubmed/35386104
http://dx.doi.org/10.1016/j.csbj.2022.03.008