Cargando…
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy
Podocyte damage is strongly associated with the progression of diabetic nephropathy. Mitotic catastrophe plays an essential role in accelerating podocyte loss and detachment from the glomerular basement membrane. In the current study, we observed that the long non-coding RNA (lncRNA) MIAT was notice...
Autores principales: | Wang, Ziyang, Chang, Ying, Liu, Yue, Liu, Bing, Zhen, Junhui, Li, Xiaobing, Lin, Jiangong, Yu, Qun, Lv, Zhimei, Wang, Rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956887/ https://www.ncbi.nlm.nih.gov/pubmed/35402074 http://dx.doi.org/10.1016/j.omtn.2022.03.001 |
Ejemplares similares
-
LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose‐induced podocyte injury via its interplay with β‐catenin
por: Hu, Mengsi, et al.
Publicado: (2017) -
Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice
por: Lv, Zhimei, et al.
Publicado: (2018) -
FAK contributes to proteinuria in hypercholesterolaemic rats and modulates podocyte F‐actin re‐organization via activating p38 in response to ox‐LDL
por: Hu, Mengsi, et al.
Publicado: (2016) -
LncRNA-MIAT Increased in Patients with Coronary Atherosclerotic Heart Disease
por: Tan, Jin, et al.
Publicado: (2019) -
Ablation of lncRNA Miat attenuates pathological hypertrophy and heart failure
por: Yang, Liu, et al.
Publicado: (2021)