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Acute exposure to environmentally relevant levels of DDT alters muscle mitochondrial function in vivo in rats but not in vitro in L6 myotubes: A pilot study

Under insulin-stimulated conditions, skeletal muscle is the largest glucose consumer in the body. Mitochondrial dysfunction and damage to this tissue from oxidative stress are linked to the pathogenesis of type 2 diabetes. Environmental exposure to dichlorodiphenyltrichloroethane (DDT) and its metab...

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Detalles Bibliográficos
Autores principales: Chehade, Lucia, Khouri, Hannah, Malatier--Ségard, Julie, Caron, Audrey, Mauger, Jean-François, Chapados, Natalie Ann, Aguer, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956919/
https://www.ncbi.nlm.nih.gov/pubmed/35345859
http://dx.doi.org/10.1016/j.toxrep.2022.03.004