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Force-feeding malignant mesothelioma stem-cell like with exosome-delivered miR-126 induces tumour cell killing

Malignant pleural mesothelioma (MPM) is an aggressive tumour resistant to treatments. It has been postulated that cancer stem cells (CSCs) persist in tumours causing relapse after multimodality treatment. In the present study, a novel miRNA-based therapy approach is proposed. MPM-derived spheroids h...

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Detalles Bibliográficos
Autores principales:	Monaco, Federica, De Conti, Laura, Vodret, Simone, Zanotta, Nunzia, Comar, Manola, Manzotti, Sandra, Rubini, Corrado, Graciotti, Laura, Fulgenzi, Gianluca, Bovenzi, Massimo, Baralle, Marco, Tomasetti, Marco, Santarelli, Lory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956928/ https://www.ncbi.nlm.nih.gov/pubmed/35334283 http://dx.doi.org/10.1016/j.tranon.2022.101400

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