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Prevention of Triglyceridemia by (Non-)Anticoagulant Heparin(oids) Does Not Preclude Transplant Vasculopathy and Glomerulosclerosis

Background: In renal transplantation, chronic transplant dysfunction (CTD) is associated with increased PCSK9 and dyslipidemia. PCSK9 is an enzyme that increases plasma cholesterol levels by downregulating LDLR expression. We recently showed increased PCSK9–syndecan-1 interaction in conditions of pr...

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Detalles Bibliográficos
Autores principales: Shrestha, Pragyi, Katta, Kirankumar, Talsma, Ditmer, Naggi, Annamaria, Hillebrands, Jan-Luuk, van de Sluis, Bart, van den Born, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957085/
https://www.ncbi.nlm.nih.gov/pubmed/35345850
http://dx.doi.org/10.3389/fcell.2022.798088