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Prevention of Triglyceridemia by (Non-)Anticoagulant Heparin(oids) Does Not Preclude Transplant Vasculopathy and Glomerulosclerosis
Background: In renal transplantation, chronic transplant dysfunction (CTD) is associated with increased PCSK9 and dyslipidemia. PCSK9 is an enzyme that increases plasma cholesterol levels by downregulating LDLR expression. We recently showed increased PCSK9–syndecan-1 interaction in conditions of pr...
Autores principales: | Shrestha, Pragyi, Katta, Kirankumar, Talsma, Ditmer, Naggi, Annamaria, Hillebrands, Jan-Luuk, van de Sluis, Bart, van den Born, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957085/ https://www.ncbi.nlm.nih.gov/pubmed/35345850 http://dx.doi.org/10.3389/fcell.2022.798088 |
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