OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer

BACKGROUND: Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans-differentiation process. Epithelial-to-Mesenchymal Transition (EMT) is recognized as one of the major players of this process...

Descripción completa

Detalles Bibliográficos
Autores principales: Gugnoni, Mila, Manzotti, Gloria, Vitale, Emanuele, Sauta, Elisabetta, Torricelli, Federica, Reggiani, Francesca, Pistoni, Mariaelena, Piana, Simonetta, Ciarrocchi, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957195/
https://www.ncbi.nlm.nih.gov/pubmed/35337349
http://dx.doi.org/10.1186/s13046-022-02316-2

Ejemplares similares

Ejemplares similares