Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets

There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, ma...

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Detalles Bibliográficos
Autor principal: Fellner, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957240/
https://www.ncbi.nlm.nih.gov/pubmed/35350120
http://dx.doi.org/10.5599/admet.1137
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author Fellner, Matthias
author_facet Fellner, Matthias
author_sort Fellner, Matthias
collection PubMed
description There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.
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spelling pubmed-89572402022-03-28 Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets Fellner, Matthias ADMET DMPK Review There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. International Association of Physical Chemists 2021-10-28 /pmc/articles/PMC8957240/ /pubmed/35350120 http://dx.doi.org/10.5599/admet.1137 Text en Copyright © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Fellner, Matthias
Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title_full Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title_fullStr Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title_full_unstemmed Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title_short Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
title_sort newly discovered staphylococcus aureus serine hydrolase probe and drug targets
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957240/
https://www.ncbi.nlm.nih.gov/pubmed/35350120
http://dx.doi.org/10.5599/admet.1137
work_keys_str_mv AT fellnermatthias newlydiscoveredstaphylococcusaureusserinehydrolaseprobeanddrugtargets

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