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Building in-house PBPK modelling tools for oral drug administration from literature information

The interest in using physiologically-based pharmacokinetic (PBPK) models as a support to the drug development decision making process has rapidly increased in the last years. These kind of models are examples of the “bottom up” modelling strategy, which progressively integrates into a mechanistic f...

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Detalles Bibliográficos
Autores principales: Grandoni, Silvia, Cesari, Nicola, Brogin, Giandomenico, Puccini, Paola, Magni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957249/
https://www.ncbi.nlm.nih.gov/pubmed/35350741
http://dx.doi.org/10.5599/admet.638