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Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study

Background and objective Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia. It is linked with an increase in morbidity (e.g., blindness, kidney failure, stroke, cardiovascular diseases, limb amputations), premature mortality, high healthcare costs, and is...

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Autores principales: Al Ghadeer, Hussain A, AlRamadan, Mohammed S, Al Amer, Mohammed M, Alshawaf, Meshal J, Alali, Fatimah J, Bubshait, Aisha A, Alramadhan, Maryam A, Almurayhil, Zainab, Aldandan, Nasser S, AlKhamis, Mohammed A, AlHaddad, Habeeb A, AlOmair, Abdulatif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957286/
https://www.ncbi.nlm.nih.gov/pubmed/35345711
http://dx.doi.org/10.7759/cureus.22558
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author Al Ghadeer, Hussain A
AlRamadan, Mohammed S
Al Amer, Mohammed M
Alshawaf, Meshal J
Alali, Fatimah J
Bubshait, Aisha A
Alramadhan, Maryam A
Almurayhil, Zainab
Aldandan, Nasser S
AlKhamis, Mohammed A
AlHaddad, Habeeb A
AlOmair, Abdulatif
author_facet Al Ghadeer, Hussain A
AlRamadan, Mohammed S
Al Amer, Mohammed M
Alshawaf, Meshal J
Alali, Fatimah J
Bubshait, Aisha A
Alramadhan, Maryam A
Almurayhil, Zainab
Aldandan, Nasser S
AlKhamis, Mohammed A
AlHaddad, Habeeb A
AlOmair, Abdulatif
author_sort Al Ghadeer, Hussain A
collection PubMed
description Background and objective Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia. It is linked with an increase in morbidity (e.g., blindness, kidney failure, stroke, cardiovascular diseases, limb amputations), premature mortality, high healthcare costs, and is quickly becoming a global epidemic disorder. Several studies have shown that vitamin D supplements reduce insulin resistance in T2DM and improve insulin secretion and sensitivity. In this study, we aimed to determine the prevalence of vitamin D deficiency in T2DM patients in Saudi Arabia. Methods This was a retrospective cross-sectional study conducted at the King Faisal University Health Centre in Saudi Arabia. The study used patient data during the period from October 2014 to January 2021. After obtaining approval from the King Faisal University Polyclinic Administration, we collected patient data from the King Faisal University Health Centre. The Ethics and Research Committee at the College of Medicine of King Faisal University granted ethical approval with the approval number (2020-11-82). The relevant patient data were collected, including age, gender, nationality, and blood test findings (vitamin D and HbA1c levels). Results A total of 191 T2DM patients participated in this study. The mean age of the patients was 56.1 ± 11.4 years (range: 21-85 years); 107 (56%) patients were females, and 137 (71.7%) were Saudis. There were 134 (70.2%) patients with vitamin D deficiency, 53 (27.7%) with vitamin D insufficiency, and only four (2.1%) with normal vitamin D levels. Conclusion Based on our findings, the prevalence of vitamin D deficiency among T2DM patients is highly associated with poor diabetic control.
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spelling pubmed-89572862022-03-27 Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study Al Ghadeer, Hussain A AlRamadan, Mohammed S Al Amer, Mohammed M Alshawaf, Meshal J Alali, Fatimah J Bubshait, Aisha A Alramadhan, Maryam A Almurayhil, Zainab Aldandan, Nasser S AlKhamis, Mohammed A AlHaddad, Habeeb A AlOmair, Abdulatif Cureus Internal Medicine Background and objective Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia. It is linked with an increase in morbidity (e.g., blindness, kidney failure, stroke, cardiovascular diseases, limb amputations), premature mortality, high healthcare costs, and is quickly becoming a global epidemic disorder. Several studies have shown that vitamin D supplements reduce insulin resistance in T2DM and improve insulin secretion and sensitivity. In this study, we aimed to determine the prevalence of vitamin D deficiency in T2DM patients in Saudi Arabia. Methods This was a retrospective cross-sectional study conducted at the King Faisal University Health Centre in Saudi Arabia. The study used patient data during the period from October 2014 to January 2021. After obtaining approval from the King Faisal University Polyclinic Administration, we collected patient data from the King Faisal University Health Centre. The Ethics and Research Committee at the College of Medicine of King Faisal University granted ethical approval with the approval number (2020-11-82). The relevant patient data were collected, including age, gender, nationality, and blood test findings (vitamin D and HbA1c levels). Results A total of 191 T2DM patients participated in this study. The mean age of the patients was 56.1 ± 11.4 years (range: 21-85 years); 107 (56%) patients were females, and 137 (71.7%) were Saudis. There were 134 (70.2%) patients with vitamin D deficiency, 53 (27.7%) with vitamin D insufficiency, and only four (2.1%) with normal vitamin D levels. Conclusion Based on our findings, the prevalence of vitamin D deficiency among T2DM patients is highly associated with poor diabetic control. Cureus 2022-02-24 /pmc/articles/PMC8957286/ /pubmed/35345711 http://dx.doi.org/10.7759/cureus.22558 Text en Copyright © 2022, Al Ghadeer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Al Ghadeer, Hussain A
AlRamadan, Mohammed S
Al Amer, Mohammed M
Alshawaf, Meshal J
Alali, Fatimah J
Bubshait, Aisha A
Alramadhan, Maryam A
Almurayhil, Zainab
Aldandan, Nasser S
AlKhamis, Mohammed A
AlHaddad, Habeeb A
AlOmair, Abdulatif
Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title_full Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title_fullStr Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title_full_unstemmed Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title_short Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study
title_sort vitamin d serum levels in type 2 diabetic patients: a cross-sectional study
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957286/
https://www.ncbi.nlm.nih.gov/pubmed/35345711
http://dx.doi.org/10.7759/cureus.22558
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