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Conserved protein targets for developing pan-coronavirus drugs based on sequence and 3D structure similarity analyses

There are 7 known human pathogenic coronaviruses, which are HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, MERS-CoV, SARS-CoV and SARS-CoV-2. While SARS-CoV-2 is currently caused a severe epidemic, experts believe that new pathogenic coronavirus would emerge in the future. Therefore, developing broad-s...

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Detalles Bibliográficos
Autores principales: Ma, Minfei, Yang, Yanqing, Wu, Leyun, Zhou, Liping, Shi, Yulong, Han, Jiaxin, Xu, Zhijian, Zhu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957316/
https://www.ncbi.nlm.nih.gov/pubmed/35364304
http://dx.doi.org/10.1016/j.compbiomed.2022.105455