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Agmatine Alleviates Cisplatin-Induced Ototoxicity by Activating PI3K/AKT Signaling Pathway

Cisplatin-induced ototoxicity can be partially attributed to excessive reactive oxygen species (ROS) production, and agmatine is well-known for the activation of the phosphoinositide-3-kinase (PI3K)/protein kinase B (AKT) pathway to inhibit ROS production. Whether agmatine could be used to alleviate...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Lv, Zhe, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957377/
https://www.ncbi.nlm.nih.gov/pubmed/35256453
http://dx.doi.org/10.1523/ENEURO.0434-21.2022

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