Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report

The management of pregnancy and delivery in patients with Glanzmann thrombasthenia requires platelet transfusion and recombinant activated factor VII. We report two successful pregnancies in a single patient and propose a protocol for monitoring and treatment. The urgent need for controlled trials a...

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Detalles Bibliográficos
Autores principales: Enciso, Leonardo, Aragón-Mendoza, Rafael L, León, Laura A, Torres-Torres, Carrie G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957384/
https://www.ncbi.nlm.nih.gov/pubmed/35355542
http://dx.doi.org/10.7759/cureus.22570
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author Enciso, Leonardo
Aragón-Mendoza, Rafael L
León, Laura A
Torres-Torres, Carrie G
author_facet Enciso, Leonardo
Aragón-Mendoza, Rafael L
León, Laura A
Torres-Torres, Carrie G
author_sort Enciso, Leonardo
collection PubMed
description The management of pregnancy and delivery in patients with Glanzmann thrombasthenia requires platelet transfusion and recombinant activated factor VII. We report two successful pregnancies in a single patient and propose a protocol for monitoring and treatment. The urgent need for controlled trials and other epidemiological studies is also underscored.
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spelling pubmed-89573842022-03-29 Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report Enciso, Leonardo Aragón-Mendoza, Rafael L León, Laura A Torres-Torres, Carrie G Cureus Internal Medicine The management of pregnancy and delivery in patients with Glanzmann thrombasthenia requires platelet transfusion and recombinant activated factor VII. We report two successful pregnancies in a single patient and propose a protocol for monitoring and treatment. The urgent need for controlled trials and other epidemiological studies is also underscored. Cureus 2022-02-24 /pmc/articles/PMC8957384/ /pubmed/35355542 http://dx.doi.org/10.7759/cureus.22570 Text en Copyright © 2022, Enciso et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Enciso, Leonardo
Aragón-Mendoza, Rafael L
León, Laura A
Torres-Torres, Carrie G
Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title_full Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title_fullStr Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title_full_unstemmed Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title_short Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report
title_sort pregnancy and delivery management with recombinant factor viia in a glanzmann thrombasthenia patient: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957384/
https://www.ncbi.nlm.nih.gov/pubmed/35355542
http://dx.doi.org/10.7759/cureus.22570
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