miR-542-3p-Targeted PDE4D Regulates cAMP/PKA Signaling Pathway and Improves Cardiomyocyte Injury

OBJECTIVE: To investigate the protective effect of miR-542-3p on cardiomyocyte injury and related mechanisms. METHODS: A cardiomyocyte hypoxia/reoxygenation model was established. The expression levels of miR-542-3p and PDE4D were detected using qRT-PCR; the luciferase reporter assay system was used...

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Detalles Bibliográficos
Autores principales: Lu, Yu, Wu, HuaJun, Deng, Min, Huang, MingDe, Pan, HaiHua, Yang, PingShao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957470/
https://www.ncbi.nlm.nih.gov/pubmed/35360268
http://dx.doi.org/10.1155/2022/7021200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957470/
https://www.ncbi.nlm.nih.gov/pubmed/35360268
http://dx.doi.org/10.1155/2022/7021200

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