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miR-542-3p-Targeted PDE4D Regulates cAMP/PKA Signaling Pathway and Improves Cardiomyocyte Injury
OBJECTIVE: To investigate the protective effect of miR-542-3p on cardiomyocyte injury and related mechanisms. METHODS: A cardiomyocyte hypoxia/reoxygenation model was established. The expression levels of miR-542-3p and PDE4D were detected using qRT-PCR; the luciferase reporter assay system was used...
Autores principales: | Lu, Yu, Wu, HuaJun, Deng, Min, Huang, MingDe, Pan, HaiHua, Yang, PingShao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957470/ https://www.ncbi.nlm.nih.gov/pubmed/35360268 http://dx.doi.org/10.1155/2022/7021200 |
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