CRISPR-Cas13a cascade-based viral RNA assay for detecting SARS-CoV-2 and its mutations in clinical samples

SARS-CoV-2 is one of the greatest threats to global human health. Point-of-care diagnostic tools for SARS-CoV-2 could facilitate rapid therapeutic intervention and mitigate transmission. In this work, we report CRISPR-Cas13a cascade-based viral RNA (Cas13C) assay for label-free and isothermal determ...

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Detalles Bibliográficos
Autores principales: Wang, Yuxi, Xue, Ting, Wang, Minjin, Ledesma-Amaro, Rodrigo, Lu, Ying, Hu, Xinyue, Zhang, Ting, Yang, Ming, Li, Yalun, Xiang, Jin, Deng, Ruijie, Ying, Binwu, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957482/
https://www.ncbi.nlm.nih.gov/pubmed/35370361
http://dx.doi.org/10.1016/j.snb.2022.131765

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