Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms

Despite their importance in tissue homeostasis and renewal, human pituitary stem cells (PSCs) are incompletely characterized. We describe a human single nucleus RNA-seq and ATAC-seq resource from pediatric, adult, and aged postmortem pituitaries (snpituitaryatlas.princeton.edu) and characterize cell...

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Detalles Bibliográficos
Autores principales: Zhang, Zidong, Zamojski, Michel, Smith, Gregory R., Willis, Thea L., Yianni, Val, Mendelev, Natalia, Pincas, Hanna, Seenarine, Nitish, Amper, Mary Anne S., Vasoya, Mital, Cheng, Wan Sze, Zaslavsky, Elena, Nair, Venugopalan D., Turgeon, Judith L., Bernard, Daniel J., Troyanskaya, Olga G., Andoniadou, Cynthia L., Sealfon, Stuart C., Ruf-Zamojski, Frederique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957708/
https://www.ncbi.nlm.nih.gov/pubmed/35263594
http://dx.doi.org/10.1016/j.celrep.2022.110467

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