The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids

Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a...

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Detalles Bibliográficos
Autores principales: Selvaraj, Vijairam, Finn, Arkadiy, Li, Jennifer, Dapaah-Afriyie, Kwame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958274/
https://www.ncbi.nlm.nih.gov/pubmed/35371682
http://dx.doi.org/10.7759/cureus.22614
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author Selvaraj, Vijairam
Finn, Arkadiy
Li, Jennifer
Dapaah-Afriyie, Kwame
author_facet Selvaraj, Vijairam
Finn, Arkadiy
Li, Jennifer
Dapaah-Afriyie, Kwame
author_sort Selvaraj, Vijairam
collection PubMed
description Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a subset of post-COVID-19 patients who present with some symptoms characteristic of MIS in adults (MIS-A) yet do not meet all the criteria for a diagnosis. We describe the unique case of a patient with this kind of presentation who clinically improved following tocilizumab and corticosteroid usage.
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spelling pubmed-89582742022-03-31 The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids Selvaraj, Vijairam Finn, Arkadiy Li, Jennifer Dapaah-Afriyie, Kwame Cureus Internal Medicine Hyperinflammation is a key component of severe coronavirus disease 2019 (COVID-19) and is associated with poor outcomes. It is imperative to distinguish severe COVID-19 from hyperinflammatory syndromes such as multisystem inflammatory syndrome (MIS) and hemophagocytic lymphohistiocytosis. There is a subset of post-COVID-19 patients who present with some symptoms characteristic of MIS in adults (MIS-A) yet do not meet all the criteria for a diagnosis. We describe the unique case of a patient with this kind of presentation who clinically improved following tocilizumab and corticosteroid usage. Cureus 2022-02-25 /pmc/articles/PMC8958274/ /pubmed/35371682 http://dx.doi.org/10.7759/cureus.22614 Text en Copyright © 2022, Selvaraj et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Selvaraj, Vijairam
Finn, Arkadiy
Li, Jennifer
Dapaah-Afriyie, Kwame
The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title_full The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title_fullStr The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title_full_unstemmed The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title_short The Treatment of COVID-19 Purgatory Syndrome With Tocilizumab and Steroids
title_sort treatment of covid-19 purgatory syndrome with tocilizumab and steroids
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958274/
https://www.ncbi.nlm.nih.gov/pubmed/35371682
http://dx.doi.org/10.7759/cureus.22614
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