Cargando…
Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OB...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958335/ https://www.ncbi.nlm.nih.gov/pubmed/35341332 http://dx.doi.org/10.1177/03946320221085465 |
_version_ | 1784676922144325632 |
---|---|
author | Hwaiz, Rundk Ahmad Zaki Abdullah, Sahar Mohammed Jalal Balaky, Salah Tofik Ali, Katan Sabir Merza, Mohammed Yousif Khailani, Shakhawan Assad Shabila, Nazar Pauls |
author_facet | Hwaiz, Rundk Ahmad Zaki Abdullah, Sahar Mohammed Jalal Balaky, Salah Tofik Ali, Katan Sabir Merza, Mohammed Yousif Khailani, Shakhawan Assad Shabila, Nazar Pauls |
author_sort | Hwaiz, Rundk Ahmad |
collection | PubMed |
description | BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OBJECTIVE: To describe and analyze the clinical and hematological characteristics of 300 hospitalized COVID-19 patients in Erbil, Kurdistan. METHODS: This retrospective study included 300 patients of any age admitted to hospital due to confirmed COVID-19 between September 2020 and February 2021. Cases were diagnosed by reverse transcriptase polymerase chain reaction assays of nasopharyngeal swab specimens. RESULTS: The highest proportion of patients were aged 21–40 years. The most common symptoms among the patients were myalgia (66.7%), fatigue (62.3%), headache (50.7%), and chest pain (52.7%). Differences in hematological and biochemical parameters were observed between deceased and recovered patients. Only the mid-range absolute count percentage (MID%) was significantly higher in the recovered patients than in the deceased ones (6.41% vs. 4.48, p = 0.019). Death was significantly higher among older patients (>40 years) than younger ones (≤40 years) (6.8% vs. 1.3%, p = 0.015), diabetic than non-diabetic (10.8% vs. 3%, p = 0.047), and those having chronic diseases than those without chronic diseases (10.6% vs. 2.1%, p = 0.006). CONCLUSIONS: Different hematological and biochemical parameter findings were observed among the COVID-19 patients. Low MID%, older age, and presence of diabetes mellitus and chronic disease were significantly associated with death among COVID-19 patients. |
format | Online Article Text |
id | pubmed-8958335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-89583352022-03-29 Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq Hwaiz, Rundk Ahmad Zaki Abdullah, Sahar Mohammed Jalal Balaky, Salah Tofik Ali, Katan Sabir Merza, Mohammed Yousif Khailani, Shakhawan Assad Shabila, Nazar Pauls Int J Immunopathol Pharmacol Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OBJECTIVE: To describe and analyze the clinical and hematological characteristics of 300 hospitalized COVID-19 patients in Erbil, Kurdistan. METHODS: This retrospective study included 300 patients of any age admitted to hospital due to confirmed COVID-19 between September 2020 and February 2021. Cases were diagnosed by reverse transcriptase polymerase chain reaction assays of nasopharyngeal swab specimens. RESULTS: The highest proportion of patients were aged 21–40 years. The most common symptoms among the patients were myalgia (66.7%), fatigue (62.3%), headache (50.7%), and chest pain (52.7%). Differences in hematological and biochemical parameters were observed between deceased and recovered patients. Only the mid-range absolute count percentage (MID%) was significantly higher in the recovered patients than in the deceased ones (6.41% vs. 4.48, p = 0.019). Death was significantly higher among older patients (>40 years) than younger ones (≤40 years) (6.8% vs. 1.3%, p = 0.015), diabetic than non-diabetic (10.8% vs. 3%, p = 0.047), and those having chronic diseases than those without chronic diseases (10.6% vs. 2.1%, p = 0.006). CONCLUSIONS: Different hematological and biochemical parameter findings were observed among the COVID-19 patients. Low MID%, older age, and presence of diabetes mellitus and chronic disease were significantly associated with death among COVID-19 patients. SAGE Publications 2022-03-27 /pmc/articles/PMC8958335/ /pubmed/35341332 http://dx.doi.org/10.1177/03946320221085465 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article Hwaiz, Rundk Ahmad Zaki Abdullah, Sahar Mohammed Jalal Balaky, Salah Tofik Ali, Katan Sabir Merza, Mohammed Yousif Khailani, Shakhawan Assad Shabila, Nazar Pauls Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq |
title | Clinical and hematological characteristics of 300 COVID-19 patients
in Erbil, Kurdistan Region, Iraq |
title_full | Clinical and hematological characteristics of 300 COVID-19 patients
in Erbil, Kurdistan Region, Iraq |
title_fullStr | Clinical and hematological characteristics of 300 COVID-19 patients
in Erbil, Kurdistan Region, Iraq |
title_full_unstemmed | Clinical and hematological characteristics of 300 COVID-19 patients
in Erbil, Kurdistan Region, Iraq |
title_short | Clinical and hematological characteristics of 300 COVID-19 patients
in Erbil, Kurdistan Region, Iraq |
title_sort | clinical and hematological characteristics of 300 covid-19 patients
in erbil, kurdistan region, iraq |
topic | Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958335/ https://www.ncbi.nlm.nih.gov/pubmed/35341332 http://dx.doi.org/10.1177/03946320221085465 |
work_keys_str_mv | AT hwaizrundkahmad clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT zakiabdullahsaharmohammed clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT jalalbalakysalahtofik clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT alikatansabir clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT merzamohammedyousif clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT khailanishakhawanassad clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq AT shabilanazarpauls clinicalandhematologicalcharacteristicsof300covid19patientsinerbilkurdistanregioniraq |