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Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq

BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OB...

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Autores principales: Hwaiz, Rundk Ahmad, Zaki Abdullah, Sahar Mohammed, Jalal Balaky, Salah Tofik, Ali, Katan Sabir, Merza, Mohammed Yousif, Khailani, Shakhawan Assad, Shabila, Nazar Pauls
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958335/
https://www.ncbi.nlm.nih.gov/pubmed/35341332
http://dx.doi.org/10.1177/03946320221085465
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author Hwaiz, Rundk Ahmad
Zaki Abdullah, Sahar Mohammed
Jalal Balaky, Salah Tofik
Ali, Katan Sabir
Merza, Mohammed Yousif
Khailani, Shakhawan Assad
Shabila, Nazar Pauls
author_facet Hwaiz, Rundk Ahmad
Zaki Abdullah, Sahar Mohammed
Jalal Balaky, Salah Tofik
Ali, Katan Sabir
Merza, Mohammed Yousif
Khailani, Shakhawan Assad
Shabila, Nazar Pauls
author_sort Hwaiz, Rundk Ahmad
collection PubMed
description BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OBJECTIVE: To describe and analyze the clinical and hematological characteristics of 300 hospitalized COVID-19 patients in Erbil, Kurdistan. METHODS: This retrospective study included 300 patients of any age admitted to hospital due to confirmed COVID-19 between September 2020 and February 2021. Cases were diagnosed by reverse transcriptase polymerase chain reaction assays of nasopharyngeal swab specimens. RESULTS: The highest proportion of patients were aged 21–40 years. The most common symptoms among the patients were myalgia (66.7%), fatigue (62.3%), headache (50.7%), and chest pain (52.7%). Differences in hematological and biochemical parameters were observed between deceased and recovered patients. Only the mid-range absolute count percentage (MID%) was significantly higher in the recovered patients than in the deceased ones (6.41% vs. 4.48, p = 0.019). Death was significantly higher among older patients (>40 years) than younger ones (≤40 years) (6.8% vs. 1.3%, p = 0.015), diabetic than non-diabetic (10.8% vs. 3%, p = 0.047), and those having chronic diseases than those without chronic diseases (10.6% vs. 2.1%, p = 0.006). CONCLUSIONS: Different hematological and biochemical parameter findings were observed among the COVID-19 patients. Low MID%, older age, and presence of diabetes mellitus and chronic disease were significantly associated with death among COVID-19 patients.
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spelling pubmed-89583352022-03-29 Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq Hwaiz, Rundk Ahmad Zaki Abdullah, Sahar Mohammed Jalal Balaky, Salah Tofik Ali, Katan Sabir Merza, Mohammed Yousif Khailani, Shakhawan Assad Shabila, Nazar Pauls Int J Immunopathol Pharmacol Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article BACKGROUND: COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. OBJECTIVE: To describe and analyze the clinical and hematological characteristics of 300 hospitalized COVID-19 patients in Erbil, Kurdistan. METHODS: This retrospective study included 300 patients of any age admitted to hospital due to confirmed COVID-19 between September 2020 and February 2021. Cases were diagnosed by reverse transcriptase polymerase chain reaction assays of nasopharyngeal swab specimens. RESULTS: The highest proportion of patients were aged 21–40 years. The most common symptoms among the patients were myalgia (66.7%), fatigue (62.3%), headache (50.7%), and chest pain (52.7%). Differences in hematological and biochemical parameters were observed between deceased and recovered patients. Only the mid-range absolute count percentage (MID%) was significantly higher in the recovered patients than in the deceased ones (6.41% vs. 4.48, p = 0.019). Death was significantly higher among older patients (>40 years) than younger ones (≤40 years) (6.8% vs. 1.3%, p = 0.015), diabetic than non-diabetic (10.8% vs. 3%, p = 0.047), and those having chronic diseases than those without chronic diseases (10.6% vs. 2.1%, p = 0.006). CONCLUSIONS: Different hematological and biochemical parameter findings were observed among the COVID-19 patients. Low MID%, older age, and presence of diabetes mellitus and chronic disease were significantly associated with death among COVID-19 patients. SAGE Publications 2022-03-27 /pmc/articles/PMC8958335/ /pubmed/35341332 http://dx.doi.org/10.1177/03946320221085465 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article
Hwaiz, Rundk Ahmad
Zaki Abdullah, Sahar Mohammed
Jalal Balaky, Salah Tofik
Ali, Katan Sabir
Merza, Mohammed Yousif
Khailani, Shakhawan Assad
Shabila, Nazar Pauls
Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title_full Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title_fullStr Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title_full_unstemmed Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title_short Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
title_sort clinical and hematological characteristics of 300 covid-19 patients in erbil, kurdistan region, iraq
topic Inflammatory Mediators in COVID-19 and Other Diseases - Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958335/
https://www.ncbi.nlm.nih.gov/pubmed/35341332
http://dx.doi.org/10.1177/03946320221085465
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