Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer

[Image: see text] We present here the advances achieved in the development of new sulfamoylated 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives as potent steroid sulfatase (STS) inhibitors for the treatment of breast cancer. Prompted by promising biological results and in silico analysis, the i...

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Detalles Bibliográficos
Autores principales: Biernacki, Karol, Ciupak, Olga, Daśko, Mateusz, Rachon, Janusz, Kozak, Witold, Rak, Janusz, Kubiński, Konrad, Masłyk, Maciej, Martyna, Aleksandra, Śliwka-Kaszyńska, Magdalena, Wietrzyk, Joanna, Świtalska, Marta, Nocentini, Alessio, Supuran, Claudiu T., Demkowicz, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958511/
https://www.ncbi.nlm.nih.gov/pubmed/35235747
http://dx.doi.org/10.1021/acs.jmedchem.1c02220

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