Plumbagin is a NF-κB-inducing kinase inhibitor with dual anabolic and antiresorptive effects that prevents menopausal-related osteoporosis in mice

Osteoporosis is caused by enhanced bone resorption and relatively reduced bone formation. There is an unmet need to develop new agents with both antiresorptive and anabolic effects to treat osteoporosis, although drugs with either effect alone are available. A small molecular compound, plumbagin, wa...

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Detalles Bibliográficos
Autores principales: Shen, Gengyang, Liu, Xin, Lei, Wei, Duan, Rong, Yao, Zhenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958545/
https://www.ncbi.nlm.nih.gov/pubmed/35235833
http://dx.doi.org/10.1016/j.jbc.2022.101767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958545/
https://www.ncbi.nlm.nih.gov/pubmed/35235833
http://dx.doi.org/10.1016/j.jbc.2022.101767

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