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Degradation and inhibition of epigenetic regulatory protein BRD4 exacerbate Alzheimer’s disease-related neuropathology in cell models

Epigenetic regulation plays substantial roles in human pathophysiology, which provides opportunities for intervention in human disorders through the targeting of epigenetic pathways. Recently, emerging evidence from preclinical studies suggested the potential in developing therapeutics of Alzheimer’...

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Detalles Bibliográficos
Autores principales:	Zhang, Siyi, Bai, Ping, Lei, Dan, Liang, Yingxia, Zhen, Sherri, Bakiasi, Grisilda, Pang, Hao, Choi, Se Hoon, Wang, Changning, Tanzi, Rudolph E., Zhang, Can
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958546/ https://www.ncbi.nlm.nih.gov/pubmed/35248531 http://dx.doi.org/10.1016/j.jbc.2022.101794

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