Neurons undergo pathogenic metabolic reprogramming in models of familial ALS

Abstract OBJECTIVES: Normal cellular function requires a rate of ATP production sufficient to meet demand. In most neurodegenerative diseases (including Amyotrophic Lateral Sclerosis [ALS]), mitochondrial dysfunction is postulated raising the possibility of impaired ATP production and a need for com...

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Detalles Bibliográficos
Autores principales: Riechers, Sean-Patrick, Mojsilovic-Petrovic, Jelena, Belton, Tayler B., Chakrabarty, Ram P., Garjani, Mehraveh, Medvedeva, Valentina, Dalton, Casey, Wong, Yvette C., Chandel, Navdeep S., Dienel, Gerald, Kalb, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958550/
https://www.ncbi.nlm.nih.gov/pubmed/35248787
http://dx.doi.org/10.1016/j.molmet.2022.101468

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