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Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism
The 12-h clock coordinates lipid homeostasis, energy metabolism, and stress rhythms via the transcriptional regulator XBP1. However, the biochemical and physiological bases for integrated control of the 12-h clock and diverse metabolic pathways remain unclear. Here, we show that steroid receptor coa...
Autores principales: | Meng, Huan, Gonzales, Naomi M., Jung, Sung Yun, Lu, Yue, Putluri, Nagireddy, Zhu, Bokai, Dacso, Clifford C., Lonard, David M., O’Malley, Bert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958721/ https://www.ncbi.nlm.nih.gov/pubmed/35263593 http://dx.doi.org/10.1016/j.celrep.2022.110491 |
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