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A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions

The purpose of this paper is to investigate the transmission dynamics of a fractional-order mathematical model of COVID-19 including susceptible ([Formula: see text] ), exposed ([Formula: see text] ), asymptomatic infected ([Formula: see text] ), symptomatic infected ([Formula: see text] ), and reco...

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Autores principales: Ali, Zeeshan, Rabiei, Faranak, Rashidi, Mohammad M., Khodadadi, Touraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958840/
https://www.ncbi.nlm.nih.gov/pubmed/35368740
http://dx.doi.org/10.1140/epjp/s13360-022-02603-z
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author Ali, Zeeshan
Rabiei, Faranak
Rashidi, Mohammad M.
Khodadadi, Touraj
author_facet Ali, Zeeshan
Rabiei, Faranak
Rashidi, Mohammad M.
Khodadadi, Touraj
author_sort Ali, Zeeshan
collection PubMed
description The purpose of this paper is to investigate the transmission dynamics of a fractional-order mathematical model of COVID-19 including susceptible ([Formula: see text] ), exposed ([Formula: see text] ), asymptomatic infected ([Formula: see text] ), symptomatic infected ([Formula: see text] ), and recovered ([Formula: see text] ) classes named [Formula: see text] model, using the Caputo fractional derivative. Here, [Formula: see text] model describes the effect of asymptomatic and symptomatic transmissions on coronavirus disease outbreak. The existence and uniqueness of the solution are studied with the help of Schaefer- and Banach-type fixed point theorems. Sensitivity analysis of the model in terms of the variance of each parameter is examined, and the basic reproduction number [Formula: see text] to discuss the local stability at two equilibrium points is proposed. Using the Routh–Hurwitz criterion of stability, it is found that the disease-free equilibrium will be stable for [Formula: see text] whereas the endemic equilibrium becomes stable for [Formula: see text] and unstable otherwise. Moreover, the numerical simulations for various values of fractional-order are carried out with the help of the fractional Euler method. The numerical results show that asymptomatic transmission has a lower impact on the disease outbreak rather than symptomatic transmission. Finally, the simulated graph of total infected population by proposed model here is compared with the real data of second-wave infected population of COVID-19 outbreak in India.
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spelling pubmed-89588402022-03-29 A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions Ali, Zeeshan Rabiei, Faranak Rashidi, Mohammad M. Khodadadi, Touraj Eur Phys J Plus Regular Article The purpose of this paper is to investigate the transmission dynamics of a fractional-order mathematical model of COVID-19 including susceptible ([Formula: see text] ), exposed ([Formula: see text] ), asymptomatic infected ([Formula: see text] ), symptomatic infected ([Formula: see text] ), and recovered ([Formula: see text] ) classes named [Formula: see text] model, using the Caputo fractional derivative. Here, [Formula: see text] model describes the effect of asymptomatic and symptomatic transmissions on coronavirus disease outbreak. The existence and uniqueness of the solution are studied with the help of Schaefer- and Banach-type fixed point theorems. Sensitivity analysis of the model in terms of the variance of each parameter is examined, and the basic reproduction number [Formula: see text] to discuss the local stability at two equilibrium points is proposed. Using the Routh–Hurwitz criterion of stability, it is found that the disease-free equilibrium will be stable for [Formula: see text] whereas the endemic equilibrium becomes stable for [Formula: see text] and unstable otherwise. Moreover, the numerical simulations for various values of fractional-order are carried out with the help of the fractional Euler method. The numerical results show that asymptomatic transmission has a lower impact on the disease outbreak rather than symptomatic transmission. Finally, the simulated graph of total infected population by proposed model here is compared with the real data of second-wave infected population of COVID-19 outbreak in India. Springer Berlin Heidelberg 2022-03-28 2022 /pmc/articles/PMC8958840/ /pubmed/35368740 http://dx.doi.org/10.1140/epjp/s13360-022-02603-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Regular Article
Ali, Zeeshan
Rabiei, Faranak
Rashidi, Mohammad M.
Khodadadi, Touraj
A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title_full A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title_fullStr A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title_full_unstemmed A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title_short A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
title_sort fractional-order mathematical model for covid-19 outbreak with the effect of symptomatic and asymptomatic transmissions
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958840/
https://www.ncbi.nlm.nih.gov/pubmed/35368740
http://dx.doi.org/10.1140/epjp/s13360-022-02603-z
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