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Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings

BACKGROUND: Hypertension is a major risk factor for global disease burden, however, little is known regarding the profiles of patients with hypertension in Indonesian primary care settings. OBJECTIVE: This study aimed to profile medication use, adherence to medications and lifestyle modifications as...

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Autores principales: Setiadi, Adji Prayitno, Febriandini, Anita, Trinanda, Eltia, Aryaguna, Wiweka, Chusna, Irene Mutho’atin, Nurlaili, Yulia, Sunderland, Bruce, Wibowo, Yosi Irawati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958961/
https://www.ncbi.nlm.nih.gov/pubmed/35356473
http://dx.doi.org/10.7717/peerj.13171
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author Setiadi, Adji Prayitno
Febriandini, Anita
Trinanda, Eltia
Aryaguna, Wiweka
Chusna, Irene Mutho’atin
Nurlaili, Yulia
Sunderland, Bruce
Wibowo, Yosi Irawati
author_facet Setiadi, Adji Prayitno
Febriandini, Anita
Trinanda, Eltia
Aryaguna, Wiweka
Chusna, Irene Mutho’atin
Nurlaili, Yulia
Sunderland, Bruce
Wibowo, Yosi Irawati
author_sort Setiadi, Adji Prayitno
collection PubMed
description BACKGROUND: Hypertension is a major risk factor for global disease burden, however, little is known regarding the profiles of patients with hypertension in Indonesian primary care settings. OBJECTIVE: This study aimed to profile medication use, adherence to medications and lifestyle modifications as well as blood pressure control among patients with hypertension in Indonesian primary health centres (PHCs). METHODS: A cross-sectional study design used a structured data collection tool (questionnaire and checklist). Patients aged ≥18 years with a diagnosis of hypertension, and prescribed an antihypertensive medication, and attending follow-up visits in the five PHCs in Surabaya, Indonesia, during a two-week study period (May–October 2019) were included. Descriptive analyses summarised the data, while binary logistic regression provided any independent associations between adherence profiles and blood pressure control. RESULTS: Of 457 eligible patients, 276 patients consented: PHC A (n = 50/91), PHC B (n = 65/116), PHC C (n = 47/61), PHC D (n = 60/88), PHC E (n = 54/101), giving an overall response rate of 60.4%. Patients were mainly treated with a single antihypertensive medication, i.e., amlodipine (89.1%), and many had not achieved blood pressure targets (68.1%). A majority reported notable levels of non-adherence to medication (low/intermediate, 65.2%) and poor healthy lifestyle behaviours, particularly physical activity (inadequate, 87.7%) and discretionary salt use (regularly, 50.4%). Significant associations were found between low medication adherence, discretionary salt use and smoking, with blood pressure control. CONCLUSIONS: The study findings provide the evidence needed to improve the current level of sub-optimal blood pressure management among patients with hypertension in these Indonesian primary care settings. Particular emphasis should be placed on antihypertensive medication adherence and healthy lifestyle behaviours through locally tailored hypertension-related interventions.
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spelling pubmed-89589612022-03-29 Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings Setiadi, Adji Prayitno Febriandini, Anita Trinanda, Eltia Aryaguna, Wiweka Chusna, Irene Mutho’atin Nurlaili, Yulia Sunderland, Bruce Wibowo, Yosi Irawati PeerJ Cardiology BACKGROUND: Hypertension is a major risk factor for global disease burden, however, little is known regarding the profiles of patients with hypertension in Indonesian primary care settings. OBJECTIVE: This study aimed to profile medication use, adherence to medications and lifestyle modifications as well as blood pressure control among patients with hypertension in Indonesian primary health centres (PHCs). METHODS: A cross-sectional study design used a structured data collection tool (questionnaire and checklist). Patients aged ≥18 years with a diagnosis of hypertension, and prescribed an antihypertensive medication, and attending follow-up visits in the five PHCs in Surabaya, Indonesia, during a two-week study period (May–October 2019) were included. Descriptive analyses summarised the data, while binary logistic regression provided any independent associations between adherence profiles and blood pressure control. RESULTS: Of 457 eligible patients, 276 patients consented: PHC A (n = 50/91), PHC B (n = 65/116), PHC C (n = 47/61), PHC D (n = 60/88), PHC E (n = 54/101), giving an overall response rate of 60.4%. Patients were mainly treated with a single antihypertensive medication, i.e., amlodipine (89.1%), and many had not achieved blood pressure targets (68.1%). A majority reported notable levels of non-adherence to medication (low/intermediate, 65.2%) and poor healthy lifestyle behaviours, particularly physical activity (inadequate, 87.7%) and discretionary salt use (regularly, 50.4%). Significant associations were found between low medication adherence, discretionary salt use and smoking, with blood pressure control. CONCLUSIONS: The study findings provide the evidence needed to improve the current level of sub-optimal blood pressure management among patients with hypertension in these Indonesian primary care settings. Particular emphasis should be placed on antihypertensive medication adherence and healthy lifestyle behaviours through locally tailored hypertension-related interventions. PeerJ Inc. 2022-03-25 /pmc/articles/PMC8958961/ /pubmed/35356473 http://dx.doi.org/10.7717/peerj.13171 Text en ©2022 Setiadi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Cardiology
Setiadi, Adji Prayitno
Febriandini, Anita
Trinanda, Eltia
Aryaguna, Wiweka
Chusna, Irene Mutho’atin
Nurlaili, Yulia
Sunderland, Bruce
Wibowo, Yosi Irawati
Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title_full Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title_fullStr Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title_full_unstemmed Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title_short Knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in Indonesian primary care settings
title_sort knowing the gap: medication use, adherence and blood pressure control among patients with hypertension in indonesian primary care settings
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958961/
https://www.ncbi.nlm.nih.gov/pubmed/35356473
http://dx.doi.org/10.7717/peerj.13171
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