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Prediction of putative potential siRNAs for inhibiting SARS-CoV-2 strains, including variants of concern and interest

Aim: To predict siRNAs as a therapeutic intervention for highly infectious new variants of SARS-CoV-2. Methods: Conserved coding sequence regions of 11 SARS-CoV-2 proteins were used to construct siRNAs through sampling of metadata comprising 214,256 sequences. Results: Predicted siRNAs S1: 5′-UCAUUG...

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Detalles Bibliográficos
Autores principales: Saba, Abdullah Al, Adiba, Maisha, Chakraborty, Sajib, Nabi, AHM Nurun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958991/
https://www.ncbi.nlm.nih.gov/pubmed/35285248
http://dx.doi.org/10.2217/fmb-2021-0130