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Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy

OBJECTIVES: The purpose of the present study was to evaluate the postoperative analgesic efficacy of fentanyl patches versus subcutaneous tramadol after canine ovariectomy, with and without unilateral mastectomy. MATERIALS AND METHODS: A total of 40 female dogs were included in the present study, al...

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Autores principales: Cicirelli, Vincenzo, Aiudi, Giulio G., Mrenoshki, Daniela, Lacalandra, Giovanni M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959330/
https://www.ncbi.nlm.nih.gov/pubmed/34953046
http://dx.doi.org/10.1002/vms3.691
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author Cicirelli, Vincenzo
Aiudi, Giulio G.
Mrenoshki, Daniela
Lacalandra, Giovanni M
author_facet Cicirelli, Vincenzo
Aiudi, Giulio G.
Mrenoshki, Daniela
Lacalandra, Giovanni M
author_sort Cicirelli, Vincenzo
collection PubMed
description OBJECTIVES: The purpose of the present study was to evaluate the postoperative analgesic efficacy of fentanyl patches versus subcutaneous tramadol after canine ovariectomy, with and without unilateral mastectomy. MATERIALS AND METHODS: A total of 40 female dogs were included in the present study, all of which were domesticated, healthy and 4–12 years of age. The animals were divided into four groups (n = 10 per group) based on the surgery and the analgesic protocol used: the TO group only underwent ovariectomy, and received postoperative tramadol; the TM group underwent both ovariectomy and mastectomy, and received postoperative tramadol; the FO group only underwent ovariectomy, and received fentanyl patches; and the FM group underwent both ovariectomy and mastectomy, and received fentanyl patches. Postoperative pain was evaluated every 4 h for 24 h using a numeric analogue scale (NAS) and a modified Glasgow Composite Measure Pain Scale Short Form (CMPS‐SF). RESULTS: The results of the present study showed that patients in all four groups tolerated postoperative surgical stress well. Analysis of variance for repeated measures did not show significant differences in the NAS scores and in Glasgow CMPS‐SF between groups in terms of pain scores or rescue analgesia. CLINICAL SIGNIFICANCE: These results indicated that the analgesic effect of the fentanyl patch was similar to that of subcutaneous (SC) tramadol in female dogs after ovariectomy, with and without unilateral mastectomy, suggesting that the fentanyl patch may represent a valid supplementary tool for the control of postoperative pain in animals after surgery.
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spelling pubmed-89593302022-03-29 Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy Cicirelli, Vincenzo Aiudi, Giulio G. Mrenoshki, Daniela Lacalandra, Giovanni M Vet Med Sci DOGS OBJECTIVES: The purpose of the present study was to evaluate the postoperative analgesic efficacy of fentanyl patches versus subcutaneous tramadol after canine ovariectomy, with and without unilateral mastectomy. MATERIALS AND METHODS: A total of 40 female dogs were included in the present study, all of which were domesticated, healthy and 4–12 years of age. The animals were divided into four groups (n = 10 per group) based on the surgery and the analgesic protocol used: the TO group only underwent ovariectomy, and received postoperative tramadol; the TM group underwent both ovariectomy and mastectomy, and received postoperative tramadol; the FO group only underwent ovariectomy, and received fentanyl patches; and the FM group underwent both ovariectomy and mastectomy, and received fentanyl patches. Postoperative pain was evaluated every 4 h for 24 h using a numeric analogue scale (NAS) and a modified Glasgow Composite Measure Pain Scale Short Form (CMPS‐SF). RESULTS: The results of the present study showed that patients in all four groups tolerated postoperative surgical stress well. Analysis of variance for repeated measures did not show significant differences in the NAS scores and in Glasgow CMPS‐SF between groups in terms of pain scores or rescue analgesia. CLINICAL SIGNIFICANCE: These results indicated that the analgesic effect of the fentanyl patch was similar to that of subcutaneous (SC) tramadol in female dogs after ovariectomy, with and without unilateral mastectomy, suggesting that the fentanyl patch may represent a valid supplementary tool for the control of postoperative pain in animals after surgery. John Wiley and Sons Inc. 2021-12-24 /pmc/articles/PMC8959330/ /pubmed/34953046 http://dx.doi.org/10.1002/vms3.691 Text en © 2021 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle DOGS
Cicirelli, Vincenzo
Aiudi, Giulio G.
Mrenoshki, Daniela
Lacalandra, Giovanni M
Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title_full Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title_fullStr Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title_full_unstemmed Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title_short Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
title_sort fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy
topic DOGS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959330/
https://www.ncbi.nlm.nih.gov/pubmed/34953046
http://dx.doi.org/10.1002/vms3.691
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