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Drug Discovery of DKK1 Inhibitors

Dickkopf-1 (DKK1) is a well-characterized Wnt inhibitor and component of the Wnt/β-catenin signaling pathway, whose dysregulation is associated with multiple abnormal pathologies including osteoporosis, Alzheimer’s disease, diabetes, and various cancers. The Wnt signaling pathway has fundamental rol...

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Detalles Bibliográficos
Autores principales:	Jiang, Hewen, Zhang, Zongkang, Yu, Yuanyuan, Chu, Hang Yin, Yu, Sifan, Yao, Shanshan, Zhang, Ge, Zhang, Bao-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959454/ https://www.ncbi.nlm.nih.gov/pubmed/35355709 http://dx.doi.org/10.3389/fphar.2022.847387

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