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Determination of Agrin and Related Proteins Levels as a Function of Age in Human Hearts

BACKGROUND: Mature cardiomyocytes are unable to proliferate, preventing the injured adult heart from repairing itself. Studies in rodents have suggested that the extracellular matrix protein agrin promotes cardiomyocyte proliferation in the developing heart and that agrin expression is downregulated...

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Detalles Bibliográficos
Autores principales: Skeffington, Katie L., Jones, Ffion P., Suleiman, M. Saadeh, Caputo, Massimo, Brancaccio, Andrea, Bigotti, Maria Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959542/
https://www.ncbi.nlm.nih.gov/pubmed/35355976
http://dx.doi.org/10.3389/fcvm.2022.813904