Cargando…

Uncoupling the Vicious Cycle of Mechanical Stress and Inflammation in Calcific Aortic Valve Disease

Calcific aortic valve disease (CAVD) is a common acquired valvulopathy, which carries a high burden of mortality. Chronic inflammation has been postulated as the predominant pathophysiological process underlying CAVD. So far, no effective medical therapies exist to halt the progression of CAVD. This...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dayawansa, Nalin H., Baratchi, Sara, Peter, Karlheinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959593/ https://www.ncbi.nlm.nih.gov/pubmed/35355968 http://dx.doi.org/10.3389/fcvm.2022.783543

Ejemplares similares

NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease
por: Wang, Yidong, et al.
Publicado: (2021)

The Complex Interplay of Inflammation, Metabolism, Epigenetics, and Sex in Calcific Disease of the Aortic Valve
por: Ferrari, Silvia, et al.
Publicado: (2022)

Molecular and Mechanical Mechanisms of Calcification Pathology Induced by Bicuspid Aortic Valve Abnormalities
por: Kazik, Hail B., et al.
Publicado: (2021)

Organ Culture Model of Aortic Valve Calcification
por: Chester, Adrian H., et al.
Publicado: (2021)

Multi-omics of in vitro aortic valve calcification
por: Semenova, Daria, et al.
Publicado: (2022)

Autotaxin and Lipoprotein Metabolism in Calcific Aortic Valve Disease
por: Mathieu, Patrick, et al.
Publicado: (2019)

The Genetic Regulation of Aortic Valve Development and Calcific Disease
por: Menon, Vinal, et al.
Publicado: (2018)

Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells
por: Xiao, Fan, et al.
Publicado: (2021)

Potential ferroptosis key genes in calcific aortic valve disease
por: Li, Xiong-Zhi, et al.
Publicado: (2022)

Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification
por: Goto, Shinji, et al.
Publicado: (2019)

Integrated proteomic and metabolomic profile analyses of cardiac valves revealed molecular mechanisms and targets in calcific aortic valve disease
por: Fu, Bo, et al.
Publicado: (2022)

Association of aortic arch and aortic valve calcifications with cardiovascular risk in patients on maintenance hemodialysis
por: Liao, Min-Tser, et al.
Publicado: (2022)

Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease
por: Meerman, Manon, et al.
Publicado: (2021)

Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models
por: Dharmarajan, Subramanian, et al.
Publicado: (2021)

Exploration and validation of the influence of angiogenesis-related factors in aortic valve calcification
por: Kong, XiangJin, et al.
Publicado: (2023)

Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development
por: Yabusaki, Katsumi, et al.
Publicado: (2016)

Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease
por: Tandon, Ishita, et al.
Publicado: (2021)

Dissecting Calcific Aortic Valve Disease—The Role, Etiology, and Drivers of Valvular Fibrosis
por: Büttner, Petra, et al.
Publicado: (2021)

Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis
por: Hong, Christin G., et al.
Publicado: (2023)

Quantity and location of aortic valve calcification predicts paravalvular leakage after transcatheter aortic valve replacement: a systematic review and meta-analysis
por: Shi, Jiale, et al.
Publicado: (2023)

Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets
por: Hulin, Alexia, et al.
Publicado: (2018)

S2 Heart Sound Detects Aortic Valve Calcification Independent of Hemodynamic Changes in Mice
por: Dargam, Valentina, et al.
Publicado: (2022)

Identification of Key Non-coding RNAs and Transcription Factors in Calcific Aortic Valve Disease
por: Guo, Shuai, et al.
Publicado: (2022)

Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis
por: Hurchla, Michelle A., et al.
Publicado: (2012)

Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification
por: Chakrabarti, Mrinmay, et al.
Publicado: (2022)

Global burden of calcific aortic valve disease and attributable risk factors from 1990 to 2019
por: Yu, Jiaye, et al.
Publicado: (2022)

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro
por: Lobov, Arseniy A., et al.
Publicado: (2022)

Transcatheter Aortic Valve Therapy for Bicuspid Aortic Valve Stenosis
por: Dayawansa, Nalin H., et al.
Publicado: (2023)

Aortic Valve Replacement for Moderate Aortic Stenosis with Severe Calcification and Left Ventricualr Dysfunction—A Case Report and Review of the Literature
por: Narang, Nikhil, et al.
Publicado: (2017)

Association Between Lipoprotein(a) and Calcific Aortic Valve Disease: A Systematic Review and Meta-Analysis
por: Liu, Qiyu, et al.
Publicado: (2022)

Bioinformatics and Machine Learning Methods to Identify FN1 as a Novel Biomarker of Aortic Valve Calcification
por: Xiong, Tao, et al.
Publicado: (2022)

Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
por: Li, Shao-Jung, et al.
Publicado: (2022)

Clinical efficacy and safety of Cox-maze IV procedure for atrial fibrillation in patients with aortic valve calcification
por: Guo, Ruikang, et al.
Publicado: (2023)

Calcific Aortic Stenosis—A Review on Acquired Mechanisms of the Disease and Treatments
por: Zebhi, Banafsheh, et al.
Publicado: (2021)

Effects of menaquinone-7 supplementation in patients with aortic valve calcification: study protocol for a randomised controlled trial
por: Lindholt, Jes Sanddal, et al.
Publicado: (2018)

Glycosaminoglycans affect endothelial to mesenchymal transformation, proliferation, and calcification in a 3D model of aortic valve disease
por: Bramsen, Jonathan Alejandro, et al.
Publicado: (2022)

IL6 gene polymorphism association with calcific aortic valve stenosis and influence on serum levels of interleukin-6
por: Junco-Vicente, Alejandro, et al.
Publicado: (2022)

Sevelamer Attenuates Bioprosthetic Heart Valve Calcification
por: Meng, Zhen, et al.
Publicado: (2021)

HIF1A inhibitor PX-478 reduces pathological stretch-induced calcification and collagen turnover in aortic valve
por: Salim, Md Tausif, et al.
Publicado: (2022)

Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease
por: Csiki, Dávid Máté, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ju91lvv26hune413m22b6hrakv