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A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates

Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies. PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that express the surface antigen VAR2CSA and bind to chondroitin sulfate A (CSA) in the placenta. Women become PM-resistant over...

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Detalles Bibliográficos
Autores principales:	Doritchamou, Justin YA, Renn, Jonathan P, Jenkins, Bethany, Mahamar, Almahamoudou, Dicko, Alassane, Fried, Michal, Duffy, Patrick E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959597/ https://www.ncbi.nlm.nih.gov/pubmed/35103596 http://dx.doi.org/10.7554/eLife.76264

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