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Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans

The response to insufficient oxygen (hypoxia) is orchestrated by the conserved hypoxia-inducible factor (HIF). However, HIF-independent hypoxia response pathways exist that act in parallel with HIF to mediate the physiological hypoxia response. Here, we describe a hypoxia response pathway controlled...

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Detalles Bibliográficos
Autores principales: Doering, Kelsie RS, Cheng, Xuanjin, Milburn, Luke, Ratnappan, Ramesh, Ghazi, Arjumand, Miller, Dana L, Taubert, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959602/
https://www.ncbi.nlm.nih.gov/pubmed/35285794
http://dx.doi.org/10.7554/eLife.67911

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