The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)

The peripheral protein quality control (periQC) system eliminates the conformationally defective cystic fibrosis transmembrane conductance regulator (CFTR), including ∆F508-CFTR, from the plasma membrane (PM) and limits the efficacy of pharmacological therapy for cystic fibrosis (CF). The ubiquitin...

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Detalles Bibliográficos
Autores principales: Taniguchi, Shogo, Ito, Yukiko, Kiritani, Hibiki, Maruo, Asuka, Sakai, Ryohei, Ono, Yuji, Fukuda, Ryosuke, Okiyoneda, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959631/
https://www.ncbi.nlm.nih.gov/pubmed/35355508
http://dx.doi.org/10.3389/fmolb.2022.840649

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