Cargando…

A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy

AIM: Notwithstanding that unprecedented endovascular progress has been achieved in recent years, it remains unclear what is the best strategy to preserve the blood perfusion of abdominal visceral arteries and promote positive aortic remodeling in patients with distal dilatation of chronic aortic dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yiming, Li, Zhenjiang, Feng, Jiaxuan, Feng, Rui, Zhou, Jian, Jing, Zaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959700/
https://www.ncbi.nlm.nih.gov/pubmed/35355962
http://dx.doi.org/10.3389/fcvm.2022.821260
_version_ 1784677220559618048
author Li, Yiming
Li, Zhenjiang
Feng, Jiaxuan
Feng, Rui
Zhou, Jian
Jing, Zaiping
author_facet Li, Yiming
Li, Zhenjiang
Feng, Jiaxuan
Feng, Rui
Zhou, Jian
Jing, Zaiping
author_sort Li, Yiming
collection PubMed
description AIM: Notwithstanding that unprecedented endovascular progress has been achieved in recent years, it remains unclear what is the best strategy to preserve the blood perfusion of abdominal visceral arteries and promote positive aortic remodeling in patients with distal dilatation of chronic aortic dissection in abdominal visceral part (CADAV) after aortic repair. The present study developed a Road Block Strategy (RBS) to solve this conundrum. METHODS AND RESULTS: This prospective single-center clinical study included patients suffering from symptomatic distal dilatation of CADAV after aortic repair treated with RBS from January 2015 to December 2019 and followed up regularly for at least 2 years. Stent grafts were implanted first to cover distal tears and expand the true lumen. Device embolization was performed to induce proximal and distal segmental false lumen thrombosis (FLT) apart from the level of the ostia of vital branches. Successful RBS was performed in 13 patients. Significant differences were found in maximum true lumen diameter (p < 0.05), blood flow area in false lumen (FL) (p < 0.001), and the ratio of blood lumen to FL area (p < 0.05) between the pre-procedure and the latest follow-up results. No aortic rupture, vital branches occlusion, thoracic and abdominal pain, or death occurred during hospitalization and follow-up. CONCLUSIONS: Our findings suggest that RBS is feasible in treating distal dilatation of chronic aortic dissection after prior proximal repair, inducing false lumen thrombosis, preventing deterioration of aortic dissection, and maintaining the patency of abdominal visceral arteries.
format Online
Article
Text
id pubmed-8959700
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89597002022-03-29 A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy Li, Yiming Li, Zhenjiang Feng, Jiaxuan Feng, Rui Zhou, Jian Jing, Zaiping Front Cardiovasc Med Cardiovascular Medicine AIM: Notwithstanding that unprecedented endovascular progress has been achieved in recent years, it remains unclear what is the best strategy to preserve the blood perfusion of abdominal visceral arteries and promote positive aortic remodeling in patients with distal dilatation of chronic aortic dissection in abdominal visceral part (CADAV) after aortic repair. The present study developed a Road Block Strategy (RBS) to solve this conundrum. METHODS AND RESULTS: This prospective single-center clinical study included patients suffering from symptomatic distal dilatation of CADAV after aortic repair treated with RBS from January 2015 to December 2019 and followed up regularly for at least 2 years. Stent grafts were implanted first to cover distal tears and expand the true lumen. Device embolization was performed to induce proximal and distal segmental false lumen thrombosis (FLT) apart from the level of the ostia of vital branches. Successful RBS was performed in 13 patients. Significant differences were found in maximum true lumen diameter (p < 0.05), blood flow area in false lumen (FL) (p < 0.001), and the ratio of blood lumen to FL area (p < 0.05) between the pre-procedure and the latest follow-up results. No aortic rupture, vital branches occlusion, thoracic and abdominal pain, or death occurred during hospitalization and follow-up. CONCLUSIONS: Our findings suggest that RBS is feasible in treating distal dilatation of chronic aortic dissection after prior proximal repair, inducing false lumen thrombosis, preventing deterioration of aortic dissection, and maintaining the patency of abdominal visceral arteries. Frontiers Media S.A. 2022-03-09 /pmc/articles/PMC8959700/ /pubmed/35355962 http://dx.doi.org/10.3389/fcvm.2022.821260 Text en Copyright © 2022 Li, Li, Feng, Feng, Zhou and Jing. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Li, Yiming
Li, Zhenjiang
Feng, Jiaxuan
Feng, Rui
Zhou, Jian
Jing, Zaiping
A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title_full A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title_fullStr A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title_full_unstemmed A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title_short A Novel Solution for Distal Dilation of Chronic Dissection After Repair Involving Visceral Branches: The Road Block Strategy
title_sort novel solution for distal dilation of chronic dissection after repair involving visceral branches: the road block strategy
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959700/
https://www.ncbi.nlm.nih.gov/pubmed/35355962
http://dx.doi.org/10.3389/fcvm.2022.821260
work_keys_str_mv AT liyiming anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT lizhenjiang anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT fengjiaxuan anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT fengrui anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT zhoujian anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT jingzaiping anovelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT liyiming novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT lizhenjiang novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT fengjiaxuan novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT fengrui novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT zhoujian novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy
AT jingzaiping novelsolutionfordistaldilationofchronicdissectionafterrepairinvolvingvisceralbranchestheroadblockstrategy