The Impact of the Secondary Binding Pocket on the Pharmacology of Class A GPCRs

G-protein coupled receptors (GPCRs) are considered important therapeutic targets due to their pathophysiological significance and pharmacological relevance. Class A receptors represent the largest group of GPCRs that gives the highest number of validated drug targets. Endogenous ligands bind to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Egyed, Attila, Kiss, Dóra Judit, Keserű, György M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959758/
https://www.ncbi.nlm.nih.gov/pubmed/35355719
http://dx.doi.org/10.3389/fphar.2022.847788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959758/
https://www.ncbi.nlm.nih.gov/pubmed/35355719
http://dx.doi.org/10.3389/fphar.2022.847788

Ejemplares similares