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The Impact of the Secondary Binding Pocket on the Pharmacology of Class A GPCRs
G-protein coupled receptors (GPCRs) are considered important therapeutic targets due to their pathophysiological significance and pharmacological relevance. Class A receptors represent the largest group of GPCRs that gives the highest number of validated drug targets. Endogenous ligands bind to the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959758/ https://www.ncbi.nlm.nih.gov/pubmed/35355719 http://dx.doi.org/10.3389/fphar.2022.847788 |