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HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance

5-Fluorouracil (5-Fu) is one of the basic drugs in colorectal cancer (CRC) chemotherapy, and its efficacy is mainly limited by the acquisition of drug resistance. However, the underlying mechanisms remain unclear. In this study, hypoxia inducible factor 1α (HIF1α) was screened for high expression in...

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Detalles Bibliográficos
Autores principales:	Shi, Bin, Xu, Fang-Fang, Xiang, Cai-Ping, Li, Chuan-Yan, Fan, Ping, Wang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959760/ https://www.ncbi.nlm.nih.gov/pubmed/35355718 http://dx.doi.org/10.3389/fphar.2022.851401

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