PDK4 Inhibition Ameliorates Melatonin Therapy by Modulating Cerebral Metabolism and Remyelination in an EAE Demyelinating Mouse Model of Multiple Sclerosis

We recently showed that melatonin ameliorates the severity of experimental autoimmune encephalomyelitis (EAE), an animal model of MS. However, efficiency of melatonin therapy was associated with side effects, manifested by slowing down of remyelination, through increasing the inhibitory effects of b...

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Detalles Bibliográficos
Autores principales: Ghareghani, Majid, Farhadi, Zahra, Rivest, Serge, Zibara, Kazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959827/
https://www.ncbi.nlm.nih.gov/pubmed/35355991
http://dx.doi.org/10.3389/fimmu.2022.862316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959827/
https://www.ncbi.nlm.nih.gov/pubmed/35355991
http://dx.doi.org/10.3389/fimmu.2022.862316

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