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Evaluation and Application of Population Pharmacokinetic Models for Identifying Delayed Methotrexate Elimination in Patients With Primary Central Nervous System Lymphoma

Objective: Several population pharmacokinetic (popPK) models have been developed to determine the sources of methotrexate (MTX) PK variability. It remains unknown if these published models are precise enough for use or if a new model needs to be built. The aims of this study were to 1) assess the pr...

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Detalles Bibliográficos
Autores principales:	Mao, Junjun, Li, Qing, Li, Pei, Qin, Weiwei, Chen, Bobin, Zhong, Mingkang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959905/ https://www.ncbi.nlm.nih.gov/pubmed/35355729 http://dx.doi.org/10.3389/fphar.2022.817673

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