Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

The immune system represents a major barrier to cancer progression, driving the evolution of immunoregulatory interactions between malignant cells and T-cells in the tumor environment. Blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare acute leukemia with plasmacytoid dendritic cell (pDC)...

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Detalles Bibliográficos
Autores principales: DePasquale, Erica A. K., Ssozi, Daniel, Ainciburu, Marina, Good, Jonathan, Noel, Jenny, Villanueva, Martin A., Couturier, Charles P., Shalek, Alex K., Aranki, Sary F., Mallidi, Hari R., Griffin, Gabriel K., Lane, Andrew A., van Galen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960171/
https://www.ncbi.nlm.nih.gov/pubmed/35359938
http://dx.doi.org/10.3389/fimmu.2022.809414

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